In 1898 the first case of transmissible warts in the dog was reported in a scientific journal. Not until 1959, it was demonstrated that canine papillomas were based on transmission of warts by cell-free extracts. This suggested involvement of viral infection. The cloning and sequencing of the genome of canine oral papillomavirus (COPV) was finished in 1994. Recently there are more and more canine papillomaviruses been discovered and sequenced. To date there are total seven types, and the list is keep growing.

Types	Clinical Aspects	Notes
COPV (CPV1)	Oral warts, inverted papillomas	The most common canine papillomavirus Infection.
CfPV2 (CPV2)	Footpad warts, Body skin warts, Inverted papillomas, exophytic warts	The second most common canine papillomavirus infection.
CPV3	Pigmented plaques, in situ SCC
CPV4	Pigmented plaques
CPV5	Pigmented plaques
CPV6	Inverted papillomas	Closely related to CPV1
CPV7	Exophytic warts, in situ SCC	Closely related to CPV2