In 1898 the first case of transmissible warts in the dog was reported in a scientific journal. Not until 1959, it was demonstrated that canine papillomas were based on transmission of warts by cell-free extracts. This suggested involvement of viral infection. The cloning and sequencing of the genome of canine oral papillomavirus (COPV) was finished in 1994. Recently there are more and more canine papillomaviruses been discovered and sequenced. To date there are total seven types, and the list is keep growing.
Types | Clinical Aspects | Notes |
COPV (CPV1) | Oral warts, inverted papillomas | The most common canine papillomavirus Infection. |
CfPV2 (CPV2) | Footpad warts, Body skin warts, Inverted papillomas, exophytic warts | The second most common canine papillomavirus infection. |
CPV3 | Pigmented plaques, in situ SCC |
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CPV4 | Pigmented plaques |
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CPV5 | Pigmented plaques |
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CPV6 | Inverted papillomas | Closely related to CPV1 |
CPV7 | Exophytic warts, in situ SCC | Closely related to CPV2 |