In 1898 the first case of transmissible warts in the dog was reported in a scientific journal. Not until 1959, it was demonstrated that canine papillomas were based on transmission of warts by cell-free extracts. This suggested involvement of viral infection. The cloning and sequencing of the genome of canine oral papillomavirus (COPV) was finished in 1994. Recently there are more and more canine papillomaviruses been discovered and sequenced. To date there are total seven types, and the list is keep growing.

Types

Clinical Aspects

Notes

COPV (CPV1)

Oral warts, inverted papillomas

The most common canine papillomavirus Infection.

CfPV2 (CPV2)

Footpad warts, Body skin warts,

Inverted papillomas, exophytic warts

The second most common canine papillomavirus infection.

CPV3

Pigmented plaques, in situ SCC

 

CPV4

Pigmented plaques

 

CPV5

Pigmented plaques

 

CPV6

Inverted papillomas

Closely related to CPV1

CPV7

Exophytic warts, in situ SCC

Closely related to CPV2